Vitamin K1 capsules are indicated in dogs and cats to counter hypoprothrombinemia induced by ingestion of coumarin-based compounds, common ingredients of commercial rodenticides, and other drug induced hypoprothrombinemia where it is definitely shown that the result is due to interference with vitamin K metabolism, e.g. salicylates.
Vitamin K1 capsules contain phytonadione for dogs and cat. This medication is produced by various manufacturers.
DOSAGE: Administer orally at the rate of 2.5-5 mg/kg of body weight(1 tablet per each 22 pounds of body weight for lower dosage or 1 tablet per each 11 pounds of body weight for higher dosage) daily as conditions require up to 3 weeks. Frequency and amount of oral administration should be guided by regular determination of prothrombin time. The smallest effective dose should be sought to minimize the risk of adverse reactions.
WARNINGS: It is recommended that Vitamin K1 capsules be used in follow-up therapy only after administration of Vitamin K1 Injection and hospitalization is no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally. Phytonadione will not counteract the anticoagulant action of heparin. Repeated large doses of Vitamin K1 are not warranted in hepatic disease if the response to the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K1.
STORAGE: Protect product from light at all times. Keep out of reach of children. Store at room temperature.